Trajectory ML 7: From Points to Paths and Branches
Build a minimal tree baseline, understand principal curves and PAGA, and identify what pseudotime can and cannot measure.
Build a minimal tree baseline, understand principal curves and PAGA, and identify what pseudotime can and cannot measure.
Use observed sequence order to estimate transitions, infer hidden states, and separate filtering from smoothing.
Recovering hidden states and trajectories from observations, from PCA to Flow Matching, survival analysis and causality, with one synthetic dataset.
As an undergrad I opened ‘General System Theory’ expecting the ultimate design principle, and found biology instead. Half a century ago Bertalanffy said life is not matter but organization: Lenia proves it on a computer.
Is talent a blessing or a trap? An analysis of how talent conditioned by short reward cycles sabotages long-term effort, and a look beneath what we call grit, at the two engines underneath: taste and lack.
The Y chromosome and the surname are both inherited down the paternal line. That single fact was enough to recover real identities from ‘anonymous’ genomes, as shown in this 2013 Science paper.
A network with ReLU activations secretly carves input space into polytope pieces and, on each piece, collapses into exactly one affine map. This post builds that view up from a single neuron to interactive demos.
How I fixed the issue where kime Korean IME only types one character before reverting to English on AWS DCV remote desktop.
Why we keep resurrecting settled debates, and the irony of this very essay doing the same
In 1990, my father bought a computer for his five-year-old son.